{

• "prefLabel": "pyruvate dehydrogenase complex",
• -
  "synonym": [
  • "pyruvate dehydrogenase complex (lipoamide)"
  ],
• -
  "definition": [
  • "The catalytic activities of the individual components of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (acetyl-transferring) activity ; GO:0004739' (E1), 'dihydrolipoyllysine-residue acetyltransferase activity ; GO:0004742' (E2), and 'dihydrolipoyl dehydrogenase activity ; GO:0004148' (E3). The overall catalytic activity of the complex is represented by the molecular function term 'pyruvate dehydrogenase (NAD+) activity ; GO:0034604'.",
  • "A multi-enzyme complex that catalyzes the oxidative decarboxylation of pyruvate to form acetyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: pyruvate dehydrogenase (E1, which may be a homodimer or a heterotetramer of two alpha and two beta subunits, depending on species), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present."
  ],
• "cui": [ ],
• "semanticType": [ ],
• "obsolete": false,
• "created": null,
• "modified": null,
• "memberOf": [ ],
• "inScheme": [ ],
• "@id": "http://purl.obolibrary.org/obo/GO_0045254",
• "@type": "http://www.w3.org/2002/07/owl#Class",
• -
  "links": {
  • "self": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0045254",
  • "ontology": "https://data.agroportal.lirmm.fr/ontologies/EFO",
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  • "parents": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0045254/parents",
  • "descendants": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0045254/descendants",
  • "ancestors": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0045254/ancestors",
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  • "tree": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0045254/tree",
  • "notes": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0045254/notes",
  • "mappings": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0045254/mappings",
  • "ui": "http://agroportal.lirmm.fr/ontologies/EFO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0045254",
  • -
    "@context": {
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    • "ontology": "http://data.bioontology.org/metadata/Ontology",
    • "children": "http://www.w3.org/2002/07/owl#Class",
    • "parents": "http://www.w3.org/2002/07/owl#Class",
    • "descendants": "http://www.w3.org/2002/07/owl#Class",
    • "ancestors": "http://www.w3.org/2002/07/owl#Class",
    • "instances": "http://data.bioontology.org/metadata/Instance",
    • "tree": "http://www.w3.org/2002/07/owl#Class",
    • "notes": "http://data.bioontology.org/metadata/Note",
    • "mappings": "http://data.bioontology.org/metadata/Mapping",
    • "ui": "http://www.w3.org/2002/07/owl#Class"
    }
  },
• -
  "@context": {
  • "@vocab": "http://data.bioontology.org/metadata/",
  • "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
  • "synonym": "http://www.w3.org/2004/02/skos/core#altLabel",
  • "definition": "http://www.w3.org/2004/02/skos/core#definition",
  • "obsolete": "http://www.w3.org/2002/07/owl#deprecated",
  • "semanticType": "http://bioportal.bioontology.org/ontologies/umls/hasSTY",
  • "cui": "http://bioportal.bioontology.org/ontologies/umls/cui",
  • "inScheme": "http://www.w3.org/2004/02/skos/core#inScheme",
  • "created": "http://purl.org/dc/terms/created",
  • "modified": "http://purl.org/dc/terms/modified",
  • "@language": "en"
  }

}