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  • "prefLabel": "Homo sapiens cell line",
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  {
  • "prefLabel": "fibroblast derived cell line",
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  {
  • "prefLabel": "cultured cell",
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    "definition": [
    • "Note that this class was re-labeled to 'cultured cell' instead of 'cell line cell', as it intent was clarified to cover any cultured cells of multicellular and unicellular organisms. This includes cells actively being cultured, or cells that have been cultured but are stored in a quiescent state for future use. In having been cultured, cells must establish homeostasis and often replicate in a foreign environment. Accomodation of this stress initiates a selection of cells fit for such challenges, wherein necessary adaptive biochemical and.or genetic changes can occur. These changes can set them apart from the in vivo cells from which they derive, and such changes will typically accumulate and change over increasing time in culture.",
    • "A cell in vitro that is or has been maintained or propagated as part of a cell culture."
    ],
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    }
  },
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  {
  • "prefLabel": "cell",
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    "definition": [
    • "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one).",
    • "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane."
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  • "prefLabel": "cellular_component",
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    "synonym": [
    • "cellular component",
    • "cell or subcellular entity",
    • "subcellular entity"
    ],
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    "definition": [
    • "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.",
    • "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)."
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  • "prefLabel": "material entity",
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    "synonym": [
    • "material type"
    ],
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    "definition": [
    • "A material entity is an entity that exists in full during the length of time of its existence, persists through this time while maintaining its identity and has no temporal parts. For example a heart, a human, a fly, a microarray."
    ],
  • "obsolete": false,
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  },
• -
  {
  • "prefLabel": "experimental factor",
  • -
    "synonym": [
    • "ExperimentalFactor"
    ],
  • -
    "definition": [
    • "Concept naming convention is lower case natural naming with spaces, when necessary captials should be used, for example disease factor, HIV, breast carcinoma, Ewing's sarcoma",
    • "An experimental factor in Array Express which are essentially the variable aspects of an experiment design which can be used to describe an experiment, or set of experiments, in an increasingly detailed manner. This upper level class is really used to give a root class from which applications can rely on and not be tied to upper ontology classses which do change."
    ],
  • "obsolete": false,
  • "@id": "http://www.ebi.ac.uk/efo/EFO_0000001",
  • "@type": "http://www.w3.org/2002/07/owl#Class",
  • -
    "links": {
    • "self": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001",
    • "ontology": "https://data.agroportal.lirmm.fr/ontologies/EFO",
    • "children": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001/children",
    • "parents": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001/parents",
    • "descendants": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001/descendants",
    • "ancestors": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001/ancestors",
    • "instances": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001/instances",
    • "tree": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001/tree",
    • "notes": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001/notes",
    • "mappings": "https://data.agroportal.lirmm.fr/ontologies/EFO/classes/http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001/mappings",
    • "ui": "http://agroportal.lirmm.fr/ontologies/EFO?p=classes&conceptid=http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0000001",
    • -
      "@context": {
      • "self": "http://www.w3.org/2002/07/owl#Class",
      • "ontology": "http://data.bioontology.org/metadata/Ontology",
      • "children": "http://www.w3.org/2002/07/owl#Class",
      • "parents": "http://www.w3.org/2002/07/owl#Class",
      • "descendants": "http://www.w3.org/2002/07/owl#Class",
      • "ancestors": "http://www.w3.org/2002/07/owl#Class",
      • "instances": "http://data.bioontology.org/metadata/Instance",
      • "tree": "http://www.w3.org/2002/07/owl#Class",
      • "notes": "http://data.bioontology.org/metadata/Note",
      • "mappings": "http://data.bioontology.org/metadata/Mapping",
      • "ui": "http://www.w3.org/2002/07/owl#Class"
      }
    },
  • -
    "@context": {
    • "@vocab": "http://data.bioontology.org/metadata/",
    • "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
    • "synonym": "http://www.w3.org/2004/02/skos/core#altLabel",
    • "definition": "http://www.w3.org/2004/02/skos/core#definition",
    • "obsolete": "http://www.w3.org/2002/07/owl#deprecated",
    • "@language": "en"
    }
  }

]