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"synonym": [- "protein-protein complex"
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"definition": [- "A stable set of interacting proteins that can be copurified and operate as a functional unit."
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"definition": [- "Variation affecting splicing function of RNA."
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"definition": [- "Variation affecting region coding for protein in protein coding RNA."
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"definition": [- "RNA produced by degradation of processing of an RNA molecule."
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"definition": [- "Effects of a variation on RNA level."
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"definition": [- "Effect of variation on protein affinity to binding molecule(s)."
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"definition": [- "A substitution of a pyrimidine, C or T (or U), for another pyrimidine."
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"definition": [- "Epigenetic modification of histone."
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"definition": [- "Inheritance of protein or protein complex structure without involvement of genetic information."
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{- "prefLabel": "effect on catalytic RNA activity",
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"definition": [- "Variation affecting catalytic function of RNA."
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{- "prefLabel": "effect on B DNA",
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"definition": [- "Variation affecting B form of right-handed DNA."
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{- "prefLabel": "effect on DNA replication",
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"definition": [- "Variation originating from semi conservative DNA strand synthesis. The template for replication is either DNA or RNA molecule."
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/VARIO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FVariO_0154",
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{- "prefLabel": "effect on alpha helix",
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"definition": [- "Variation affecting protein helix having 3.6 residues per turn. Every backbone N-H group donates a hydrogen bond to the backbone C=O group of the amino acid four residues earlier."
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/VARIO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FVariO_0085",
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"definition": [- "Variation affecting extended protein backbone structure."
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{- "prefLabel": "effect on protein beta bulge loop",
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"definition": [- "Variation affecting protein motif of three residues within a beta-sheet consisting of two H-bonds."
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{- "prefLabel": "association of protein variation to pathogenicity",
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"definition": [- "Implication of a protein variant to pathogenicity."
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- "@id": "http://purl.obolibrary.org/obo/VariO_0047",
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- "ontology": "http://data.bioontology.org/metadata/Ontology",
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},-
"@context": {}
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{- "prefLabel": "centromeric non-coding RNA",
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"definition": [- "Non-coding RNA related to centromere."
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- "matchType": "prefLabel",
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- "@id": "http://purl.obolibrary.org/obo/VariO_0490",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/VARIO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FVariO_0490",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
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"@context": {}
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{- "prefLabel": "effect on translation",
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"definition": [- "Variation affecting translation of protein."
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/VARIO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FVariO_0399",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
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"@context": {}
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{- "prefLabel": "effect on C DNA",
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"definition": [- "Variation affecting C form of right-handed DNA."
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- "@id": "http://purl.obolibrary.org/obo/VariO_0415",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/VARIO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FVariO_0415",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
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{- "prefLabel": "isodisomy",
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"definition": [- "Uniparental disomy with duplication of a single chromosome from one parent."
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- "ontologyType": "ONTOLOGY",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/VARIO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FVariO_0210",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
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"@context": {}
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{- "prefLabel": "trisomy",
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"definition": [- "Three copies of a chromosome in a cell or organism."
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/VARIO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FVariO_0207",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
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}
},-
"@context": {}
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{- "prefLabel": "effect on RNA multiloop",
-
"definition": [- "Variation affecting closed RNA structure in which at least two double stranded regions meet."
],- "obsolete": false,
- "matchType": "prefLabel",
- "ontologyType": "ONTOLOGY",
- "@id": "http://purl.obolibrary.org/obo/VariO_0383",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/VARIO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FVariO_0383",
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"definition": [- "Variation with four sets of chromosomes."
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"definition": [- "Variation affecting L form of right-handed DNA."
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