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{- "prefLabel": "ecdysone",
-
"synonym": [- "(22R)-2beta,3beta,14alpha,22,25-pentahydroxy-5beta-cholest-7-en-6-one",
- "Ecdysone",
- "(22R)-2beta,3beta,14,22,25-pentahydroxy-5beta-cholest-7-en-6-one",
- "ecdysone",
- "(2beta,3beta,5beta,22R)-2,3,14,22,25-pentahydroxycholest-7-en-6-one"
],-
"definition": [- "A 6-oxo steroid that is 5beta-cholest-7-en-6-one substituted by hydroxy groups at positions 2, 3, 14, 22 and 25 respectively (the 2beta, 3beta, 22R stereoisomer). It is a steroid prohormone of the major insect moulting hormone 20-hydroxyecdysone."
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{- "prefLabel": "cortisone",
-
"synonym": [- "11-dehydro-17-hydroxycorticosterone",
- "Cortison",
- "Kendall's compound E",
- "17-hydroxy-11-dehydrocorticosterone",
- "17,21-dihydroxypregn-4-ene-3,11,20-trione",
- "cortisone",
- "17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione",
- "pregn-4-en-17alpha,21-diol-3,11,20-trione",
- "17alpha,21-dihydroxy-4-pregnene-3,11,20-trione",
- "Reichstein's substance Fa",
- "Delta(4)-pregnene-17alpha,21-diol-3,11,20-trione",
- "Kortison",
- "4-pregnene-17alpha,21-diol-3,11,20-trione",
- "Wintersteiner's compound F",
- "Cortisone"
],-
"definition": [- "A C21-steroid that is pregn-4-ene substituted by hydroxy groups at positions 17 and 21 and oxo group at positions 3, 11 and 20."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_16962",
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{- "prefLabel": "11-deoxycorticosterone",
-
"synonym": [- "Cortexone",
- "21-hydroxypregn-4-ene-3,20-dione",
- "21-Hydroxy-4-pregnene-3,20-dione",
- "21-hydroxyprogesterone",
- "Reichstein's substance Q",
- "DESOXYCORTICOSTERONE",
- "11-Deoxycorticosterone",
- "desoxycortone",
- "DOC",
- "4-pregnen-21-ol-3,20-dione",
- "Kendall's desoxy compound B",
- "Deoxycorticosterone",
- "Desoxycortone"
],-
"definition": [- "A mineralocorticoid that is progesterone substituted at position 21 by a hydroxy group."
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{- "prefLabel": "progesterone",
-
"synonym": [- "Gelbkoerperhormon",
- "progesterone",
- "17alpha-progesterone",
- "PROGESTERONE",
- "(S)-Progesterone",
- "4-Pregnene-3,20-dione",
- "Delta(4)-pregnene-3,20-dione",
- "(S)-Pregn-4-en-3,20-dione",
- "pregn-4-ene-3,20-dione",
- "Agolutin",
- "Progesterone",
- "(S)-4-Pregnene-3,20-dione",
- "Akrolutin",
- "Progesteron",
- "corpus luteum hormone",
- "Crinone",
- "luteohormone"
],-
"definition": [- "A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species."
],- "obsolete": false,
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{- "prefLabel": "estrone",
-
"synonym": [- "oestrone",
- "Estrone",
- "estrone",
- "3-hydroxyestra-1,3,5(10)-trien-17-one",
- "follicular hormone",
- "folliculin",
- "3-Hydroxy-1,3,5(10)-estratrien-17-one"
],-
"definition": [- "A 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_17263",
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{- "prefLabel": "testosterone",
-
"synonym": [- "17beta-hydroxy-4-androsten-3-one",
- "testosterona",
- "Testosteron",
- "testosteronum",
- "17beta-Hydroxy-4-androsten-3-one",
- "Testosterone",
- "Androderm",
- "4-androsten-17beta-ol-3-one",
- "TESTOSTERONE",
- "17beta-hydroxyandrost-4-en-3-one",
- "testosterone"
],-
"definition": [- "An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.."
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{- "prefLabel": "cortisol",
-
"synonym": [- "Cortisol",
- "11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione",
- "hidrocortisona",
- "11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione",
- "11beta,17,21-trihydroxypregn-4-ene-3,20-dione",
- "Reichstein's substance M",
- "hydrocortisone",
- "hydrocortisonum",
- "11beta-hydrocortisone",
- "4-pregnen-11beta,17alpha,21-triol-3,20-dione",
- "Hydrocortisone",
- "Kendall's compound F",
- "cortisol",
- "(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione",
- "17-hydroxycorticosterone"
],-
"definition": [- "A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the \"stress hormone\" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses"
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_17650",
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{- "prefLabel": "17-oxo steroid",
-
"synonym": [- "a 17-oxo steroid",
- "17-oxosteroid",
- "17-keto steroid",
- "17-ketosteroid",
- "17-oxo steroids",
- "17-ketosteroids",
- "17-keto steroids",
- "17-oxosteroids"
],-
"definition": [- "Any oxo steroid carrying the oxo group at position 17."
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{- "prefLabel": "3-oxo-Delta(1) steroid",
-
"synonym": [- "3-oxo Delta(1)-steroids",
- "3-keto-Delta(1) steroids",
- "3-oxo-Delta(1) steroids",
- "3-oxo-Delta(1) steroid",
- "a 3-oxo-Delta(1)-steroid",
- "3-oxo-Delta1-steroid",
- "3-oxo-Delta1-steroids",
- "3-oxo Delta(1)-steroid",
- "3-keto-Delta(1) steroid",
- "3-oxo-Delta(1)-steroids"
],-
"definition": [- "Any 3-oxo steroid that contains a double bond between positions 1 and 2."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_20156",
- "@type": "http://www.w3.org/2002/07/owl#Class",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/ECTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_20156",
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{- "prefLabel": "aldosterone",
-
"synonym": [- "Aldosterone",
- "(+)-aldosterone",
- "ALDOSTERONE",
- "11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al",
- "(11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al",
- "11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al",
- "aldosterone"
],-
"definition": [- "A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_27584",
- "@type": "http://www.w3.org/2002/07/owl#Class",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/ECTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_27584",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
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{- "prefLabel": "dehydroepiandrosterone",
-
"synonym": [- "Intrarosa",
- "3-BETA-HYDROXY-5-ANDROSTEN-17-ONE",
- "Prasterone",
- "DHA",
- "Dehydroisoandrosterone",
- "3beta-hydroxyandrost-5-en-17-one",
- "Dehydroepiandrosterone",
- "DHEA",
- "3beta-Hydroxyandrost-5-en-17-one"
],-
"definition": [- "An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_28689",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/ECTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_28689",
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{- "prefLabel": "Delta(1)-progesterone",
-
"synonym": [- "3,20-dioxo-pregna-1,4-diene",
- "delta1-Progesterone",
- "3,20-dioxo-1,4-pregnadiene",
- "Pregna-1,4-diene-3,20-dione",
- "pregna-1,4-diene-3,20-dione",
- "1,2-didehydroprogesterone",
- "1,2-dehydroprogesterone",
- "1-Dehydroprogesterone"
],-
"definition": [- "A 3-oxo Delta(4)-steroid that is progesterone which has been oxidised to introduce a double bond between positions 1 and 2."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_34073",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/ECTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_34073",
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{- "prefLabel": "6-oxo steroid",
-
"synonym": [],- "definition": [ ],
- "obsolete": false,
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{- "prefLabel": "20-oxo steroid",
-
"synonym": [],-
"definition": [- "An oxo steroid carrying an oxo group at position 20."
],- "obsolete": false,
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{- "prefLabel": "18-oxo steroid",
-
"synonym": [],- "definition": [ ],
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{- "prefLabel": "dexamethasone",
-
"synonym": [- "Decacort",
- "16alpha-methyl-9alpha-fluoro-1-dehydrocortisol",
- "dexamethasonum",
- "Decaject",
- "Ozurdex",
- "(11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione",
- "Hexadrol",
- "dexametasona",
- "Azium",
- "Dexacortal",
- "dexamethasone",
- "Decameth",
- "Oradexon",
- "Zema-Pak",
- "DexPak",
- "9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione",
- "Aeroseb-Dex",
- "1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone",
- "fluormethylprednisolone",
- "9alpha-fluoro-16alpha-methylprednisolone",
- "Diodex",
- "Millicorten",
- "Dexasone",
- "Maxidex",
- "Corson",
- "Dexason",
- "Decadron",
- "Calonat",
- "Dexamethasone",
- "Decalix",
- "Dexacortin",
- "Auxiron",
- "Solurex",
- "Cortisumman"
],-
"definition": [- "A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids."
],- "obsolete": false,
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{- "prefLabel": "11-oxo steroid",
-
"synonym": [- "11-Oxosteroid",
- "11-oxo steroids",
- "11-oxosteroids",
- "an 11-oxosteroid"
],-
"definition": [- "Any oxo steroid that has an oxo substituent at position 11."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_47787",
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{- "prefLabel": "3-oxo steroid",
-
"synonym": [- "a 3-oxosteroid",
- "3-oxo steroids",
- "3-Oxosteroid",
- "3-oxosteroids"
],-
"definition": [- "Any oxo steroid where an oxo substituent is located at position 3."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_47788",
- "@type": "http://www.w3.org/2002/07/owl#Class",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/ECTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_47788",
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{- "prefLabel": "3-oxo-Delta(4) steroid",
-
"synonym": [- "3-oxo-Delta(4) steroids",
- "3-Oxo-delta4-steroid",
- "a 3-oxo-Delta(4)-steroid",
- "3-oxo Delta(4)-steroid",
- "3-oxo Delta(4)-steroids"
],-
"definition": [- "A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/CHEBI_47909",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/ECTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_47909",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
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{- "prefLabel": "exemestane",
-
"synonym": [- "exemestane",
- "Exemestane",
- "exemestanum",
- "exemestano",
- "6-methyleneandrosta-1,4-diene-3,17-dione",
- "6-methylideneandrosta-1,4-diene-3,17-dione"
],-
"definition": [- "A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer."
],- "obsolete": false,
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/ECTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4953",
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{- "prefLabel": "6-methylprednisolone",
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"synonym": [- "11beta,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione",
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"synonym": [- "Delta(1)-6alpha-methylhydrocortisone",
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- "methylprednisolonum",
- "Medrol",
- "11beta,17,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione",
- "6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione"
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{- "prefLabel": "3-oxo-Delta(1),Delta(4)-steroid",
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"synonym": [- "3-oxo-Delta(1,4)-steroids",
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- "a 3-oxo-Delta(1,4)-steroid",
- "3-oxo Delta(1),Delta(4)-steroids",
- "3-oxo-Delta(1,4)-steroid",
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"definition": [- "A 3-oxo-Delta(1) steroid containing an additional double bond between positions 4 and 5."
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"synonym": [- "1,4-pregnadiene-3,20-dione-11beta,17alpha,21-triol",
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