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"definition": [- "A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain."
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{- "prefLabel": "ionotropic glutamate receptor complex",
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"definition": [- "A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex."
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{- "prefLabel": "B cell receptor complex",
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"synonym": [- "B lymphocyte receptor complex",
- "B-cell receptor complex",
- "B-lymphocyte receptor complex",
- "BCR complex",
- "immunoglobulin complex, membrane bound",
- "antibody",
- "B cell receptor accessory molecule complex"
],-
"definition": [- "Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.",
- "An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins."
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{- "prefLabel": "kainate selective glutamate receptor complex",
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"definition": [- "An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits."
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{- "prefLabel": "T cell receptor complex",
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"synonym": [- "T lymphocyte receptor complex",
- "T-cell receptor complex",
- "T-lymphocyte receptor complex",
- "TCR complex",
- "TCR"
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"definition": [- "A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains."
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{- "prefLabel": "alpha-beta T cell receptor complex",
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"synonym": [- "alpha-beta T lymphocyte receptor complex",
- "alpha-beta T-cell receptor complex",
- "alpha-beta T-lymphocyte receptor complex",
- "alpha-beta TCR complex"
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"definition": [- "A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein."
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{- "prefLabel": "gamma-delta T cell receptor complex",
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"synonym": [- "gamma-delta T lymphocyte receptor complex",
- "gamma-delta T-cell receptor complex",
- "gamma-delta T-lymphocyte receptor complex",
- "gamma-delta TCR complex"
],-
"definition": [- "A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein."
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{- "prefLabel": "pre-T cell receptor complex",
-
"synonym": [- "pre-T lymphocyte receptor complex",
- "pre-T-cell receptor complex",
- "pre-T-lymphocyte receptor complex",
- "pre-TCR complex"
],-
"definition": [- "A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/GO_0043384",
- "@type": "http://www.w3.org/2002/07/owl#Class",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0043384",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
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- "ui": "http://www.w3.org/2002/07/owl#Class"
}
},-
"@context": {}
},-
{- "prefLabel": "G protein-coupled receptor complex",
-
"synonym": [- "G-protein coupled receptor complex"
],-
"definition": [- "A protein complex that contains G protein-coupled receptors."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/GO_0097648",
- "@type": "http://www.w3.org/2002/07/owl#Class",
-
"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0097648",
- "ontology": "https://data.agroportal.lirmm.fr/ontologies/CL",
- "children": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0097648/children",
- "parents": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0097648/parents",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
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- "ui": "http://www.w3.org/2002/07/owl#Class"
}
},-
"@context": {}
},-
{- "prefLabel": "serotonin receptor complex",
-
"synonym": [- "5-HT receptor complex",
- "5-hydroxytryptamine receptor complex",
- "5HT receptor complex"
],-
"definition": [- "A protein complex that is capable of serotonin receptor activity."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/GO_0098665",
- "@type": "http://www.w3.org/2002/07/owl#Class",
-
"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098665",
- "ontology": "https://data.agroportal.lirmm.fr/ontologies/CL",
- "children": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098665/children",
- "parents": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098665/parents",
- "descendants": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098665/descendants",
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- "tree": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098665/tree",
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- "ui": "http://agroportal.lirmm.fr/ontologies/CL?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098665",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
- "children": "http://www.w3.org/2002/07/owl#Class",
- "parents": "http://www.w3.org/2002/07/owl#Class",
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- "mappings": "http://data.bioontology.org/metadata/Mapping",
- "ui": "http://www.w3.org/2002/07/owl#Class"
}
},-
"@context": {}
},-
{- "prefLabel": "G protein-coupled serotonin receptor complex",
-
"synonym": [- "G-protein coupled serotonin receptor complex"
],-
"definition": [- "A protein complex that is capable of G protein-coupled serotonin receptor activity."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/GO_0098666",
- "@type": "http://www.w3.org/2002/07/owl#Class",
-
"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098666",
- "ontology": "https://data.agroportal.lirmm.fr/ontologies/CL",
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- "parents": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098666/parents",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
- "children": "http://www.w3.org/2002/07/owl#Class",
- "parents": "http://www.w3.org/2002/07/owl#Class",
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- "mappings": "http://data.bioontology.org/metadata/Mapping",
- "ui": "http://www.w3.org/2002/07/owl#Class"
}
},-
"@context": {}
},-
{- "prefLabel": "plasma membrane signaling receptor complex",
- "synonym": [ ],
-
"definition": [- "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.",
- "Any protein complex that is part of the plasma membrane and which functions as a signaling receptor."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/GO_0098802",
- "@type": "http://www.w3.org/2002/07/owl#Class",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098802",
- "ontology": "https://data.agroportal.lirmm.fr/ontologies/CL",
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- "parents": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098802/parents",
- "descendants": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098802/descendants",
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- "mappings": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098802/mappings",
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-
"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
- "children": "http://www.w3.org/2002/07/owl#Class",
- "parents": "http://www.w3.org/2002/07/owl#Class",
- "descendants": "http://www.w3.org/2002/07/owl#Class",
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- "mappings": "http://data.bioontology.org/metadata/Mapping",
- "ui": "http://www.w3.org/2002/07/owl#Class"
}
},-
"@context": {}
},-
{- "prefLabel": "neurotransmitter receptor complex",
- "synonym": [ ],
-
"definition": [- "Any protein complex that is capable of functioning as a neurotransmitter receptor."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/GO_0098878",
- "@type": "http://www.w3.org/2002/07/owl#Class",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098878",
- "ontology": "https://data.agroportal.lirmm.fr/ontologies/CL",
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- "parents": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098878/parents",
- "descendants": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098878/descendants",
- "ancestors": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098878/ancestors",
- "instances": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_0098878/instances",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
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- "ui": "http://www.w3.org/2002/07/owl#Class"
}
},-
"@context": {}
},-
{- "prefLabel": "GABA receptor complex",
-
"synonym": [- "gamma-aminobutyric acid receptor complex"
],-
"definition": [- "A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/GO_1902710",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_1902710",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
- "children": "http://www.w3.org/2002/07/owl#Class",
- "parents": "http://www.w3.org/2002/07/owl#Class",
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- "mappings": "http://data.bioontology.org/metadata/Mapping",
- "ui": "http://www.w3.org/2002/07/owl#Class"
}
},-
"@context": {}
},-
{- "prefLabel": "calcitonin family receptor complex",
- "synonym": [ ],
-
"definition": [- "A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far."
],- "obsolete": false,
- "@id": "http://purl.obolibrary.org/obo/GO_1903439",
- "@type": "http://www.w3.org/2002/07/owl#Class",
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_1903439",
- "ontology": "https://data.agroportal.lirmm.fr/ontologies/CL",
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- "parents": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_1903439/parents",
- "descendants": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_1903439/descendants",
- "ancestors": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGO_1903439/ancestors",
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{- "prefLabel": "serotonin-activated cation-selective channel complex",
-
"synonym": [- "5-HT-3 receptor complex",
- "5-HT3 receptor complex",
- "5-hydroxytryptamine receptor 3 complex",
- "5HT3 receptor complex",
- "serotonin receptor complex"
],-
"definition": [- "An example of this is HTR3A in human (P46098) in PMID:16116092 (inferred from direct assay).",
- "A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist."
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}