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"definition": [- "An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier."
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{- "prefLabel": "endothelial cell of lymphatic vessel",
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"synonym": [- "LEC",
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{- "prefLabel": "glomerular endothelial cell",
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"definition": [- "Glomerular endothelial cells have 60-80 nm fenestrations typically lacking diaphragms in adults but present during embryonic development. Some studies found diaphragms in 2-6% of mature rat glomerular capillaries. Their presence may depend on fixation techniques, developmental stage, or dynamic cell changes. Additionally, these cells help maintain the structural integrity of glomerular capillaries through interactions with the basement membrane and podocytes.",
- "An endothelial cell that is part of the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate."
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{- "prefLabel": "circulating endothelial cell",
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"definition": [- "A circulating endothelial cell of the phenotype CD146-positive, CD105-positive, CD45-negative. This cell type is indicative of recent vascular damage."
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{- "prefLabel": "endothelial cell of umbilical vein",
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"definition": [- "An endothelial cell of the umbilical vein."
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{- "prefLabel": "endothelial cell of hepatic sinusoid",
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"synonym": [- "LSEC",
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- "liver sinusoidal endothelial cell"
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"definition": [- "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates."
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},-
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}
},-
{- "prefLabel": "blood vessel endothelial cell",
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"definition": [- "An endothelial cell that lines the vasculature."
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}
},-
{- "prefLabel": "fenestrated endothelial cell",
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"synonym": [],-
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}
},-
{- "prefLabel": "endothelial cell of vascular tree",
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"synonym": [- "vascular endothelial cell",
- "cubodial endothelial cell of vascular tree"
],-
"definition": [- "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive.",
- "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels."
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCL_0002139",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
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}
},-
{- "prefLabel": "endothelial cell of sinusoid",
- "synonym": [ ],
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"definition": [- "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver."
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCL_0002262",
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"@context": {- "@vocab": "http://data.bioontology.org/metadata/",
- "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
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}
},-
{- "prefLabel": "endocardial cell",
-
"synonym": [- "endocardial endothelial cell",
- "endothelial cell of endocardium"
],-
"definition": [- "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin."
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCL_0002350",
- "ontology": "https://data.agroportal.lirmm.fr/ontologies/CL",
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"@context": {- "self": "http://www.w3.org/2002/07/owl#Class",
- "ontology": "http://data.bioontology.org/metadata/Ontology",
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"@context": {- "@vocab": "http://data.bioontology.org/metadata/",
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- "modified": "http://purl.org/dc/terms/modified",
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}
},-
{- "prefLabel": "squamous endothelial cell",
- "synonym": [ ],
-
"definition": [- "A squamous shaped endothelial cell."
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCL_0002653",
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{- "prefLabel": "cardiac endothelial cell",
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{- "prefLabel": "endothelial cell of arteriole",
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{- "prefLabel": "endothelial cell of artery",
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"synonym": [- "arterial endothelial cell"
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"definition": [- "A blood vessel endothelial cell that is part of an arterial endothelium."
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{- "prefLabel": "cerebral cortex endothelial cell",
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"synonym": [- "cerebral cortex endothelial cells",
- "endothelial cells of cerebral cortex"
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"definition": [- "A distinct endothelial cell forming the walls of the capillaries within the cerebral cortex."
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{- "prefLabel": "gut endothelial cell",
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"definition": [- "An endothelial cell that lines the blood and lymphatic vessels of the digestive tract. This cell forms the gut–vascular barrier (GVB) through tight junctions and crosstalk with pericytes and enteric glial cells, regulating the passage of nutrients and immune cells while restricting microbial translocation into the bloodstream."
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{- "prefLabel": "trabecular meshwork cell",
-
"synonym": [],-
"definition": [- "A cell that lines the trabecular meshwork, which is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). This cell may play a role in regulating intraocular pressure."
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"links": {- "self": "https://data.agroportal.lirmm.fr/ontologies/CL/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCL_0002367",
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"synonym": [- "portal endothelial cell"
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{- "prefLabel": "endothelial cell of uterus",
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"synonym": [- "uterine endothelial cell"
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"definition": [- "An endothelial cell that is part of a uterus."
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{- "prefLabel": "lymph node lymphatic vessel endothelial cell",
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"definition": [- "An endothelial cell located in a lymph node lymphatic vessel."
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{- "prefLabel": "endothelial cell of venous sinus of red pulp of spleen",
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"definition": [- "todo - add logical definition to UBERON:0009967",
- "An endothelial cell that is part of the venous sinus of red pulp of spleen."
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